lunes, 12 de septiembre de 2011

Discovery of blood pressure genes could help prevent cardiovascular disease

Discovery of blood pressure genes could help prevent cardiovascular disease:



"Toby Johnson, Patricia Munroe and Mark Caulfield from Barts and The London Medical School co-led with US and European colleagues an international collaborative study involving 351 scientists from 234 institutions based in 24 countries around the world. This study analysed data on over 270,000 people to find genetic variations in the DNA of each person that were associated with higher or lower blood pressure. This enabled them to identify 16 new gene regions influencing blood pressure and provided confirmation of 12 other gene regions that had previously been discovered by the Barts and The London team"


Journal References:
  1. Wain et al. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nature Genetics, 2011; DOI:10.1038/ng.922
  2. The International Consortium for Blood Pressure Genome-Wide Association Studies. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature, 2011; DOI:

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